PeriVasc products
and methodologies

Overview

Products for peripheral vascular research

The PeriVasc is a system for flexibel cuff inflation and deflation to facilitate peripheral vascular research/investigation examinations. The PeriVasc system features air plethysmograhic (APG) set-ups, recording and data analysis. It has been founded by a group of experts (engineers and medical professionals) over the period of more than 10 years and has just recently (2024) made products, software and services commercially available.

PeriVasc Air Unit Model 01 – PVAU M01

PeriVasc Air Unit Model 01 (PVAU M01) is a versatile 2-channel air system for inflating/deflating cuffs with three states: Inflate, Deflate, and Float which supports air plethysmographic measurements.

PeriVasc Software G – PVSW G

PeriVasc Software G (PVSW G) is a PC-based software records real-time pressure data from the PVAU M01, enabling monitoring, storage and analysis air plethysmographic data.

Generic cuff inflation / deflation procedure

A cuff system could be inflated to virtually any pressure level, hold for any time and deflated. This could be repeated or executed by a built in sequence protocol in the PeriVasc Air Unit M01 to support a wide range of custom needs in research applications.

The principal of Air Plethysmography (APG)

By containing a given amount of air in a restricted volume, any change of that volume will manifest as a change pressure . Inflating a certain amount of air in a cuff and contain it is supported by the PeriVasc Air Unit M01. Pressure data is then logged and may be transferred to a PC for further analysis using the PeriVasc Software G or any custom developed software.

Using APG to quantify venous reflux in lower limb with and without occlusion of the superficial vein system

To quantify the venouse reflux (relative or absolute) a special sensor-cuff is needed at the position of interest. The sensor-cuff will be pre-filled with a specified pressure and set in a “float“ state. That is the air volume will be contained.

In the picture the sensor-cuff placed on the test subjects left foot. For this only one PVAU M01 is required, but in the same set-up there is a second PVUA M01 used to support a artificial occlusion of the superficial vein system. In such setup, a base-line recording (no occlusion of the superficaial vein system) is compared to a recording with occlusion of the superficial vein system.

The muscle pump activation is performed by, in this case, leg squats to drain the vein system of blood

After the activation the test subjects remain in a standing position for roughly 1min while the reflux of the vein blood is registred by The PVAU M01 and data transferred to the PVSW G.

The corresponding reflux curve(s) are then analyzed using the PVSW G.

Volume (plethysmographic) data recording from the set-up in the figure above The PeriVasc software has been used to record the volume change of the left (red) and right (green) foot during and after the muscle pump activation. The recording in the picture is a base-line recording (no occlusion of the superficial vein system). The reflux phase of the volume curves could then be analyzed in terms of, for instance, reflux rate (T50 and T90).